The Synthesis of D-Arabinose-1-14C and D-Ribose-1-14C.

The Biosynthesis of Polysaccharides. Incorporation of D-(1-14c)glucose and D-(6-14c)glucose into Plum-leaf Polysaccharides.

1. The utilization of specifically labelled d-glucose in the biosynthesis of plum-leaf polysaccharides has been studied. After these precursors had been metabolized in plum leaves, the polysaccharides were isolated from the leaves, and their monosaccharide constituents isolated and purified. 2. Both the specific activities and the distribution of (14)C along the carbon chains of the monosacchar...

Metabolism of D-cephaloglycin-14C and L-cephaloglycin-14C in the rat.

The fate of the orally effective antibiotic D-cephaloglycin and its much less active L-enantiomer has been studied in the rat. D-Cephaloglycin-14C is metabolized by two pathways, (1) hydrolysis of the amide linkage to form D-2-phenylglycine-14C and (2) deacetylation to form deacetyl-D-cephaloglycinUC. D-Cephaloglycin is absorbed from the gastro-intestinal tract at least in part as the intact an...

The fate of 14C in glucose 6-phosphate synthesized from [1-14C]Ribose 5-phosphate by enzymes of rat liver.

1. Glucose 5-phosphate was synthesized from ribose 5-phosphate by an enzyme extract prepared from an acetone-dried powder of rat liver. Three rates of ribose 5-phosphate utilization were observed during incubation for 17 h. An analysis of intermediates and products formed throughout the incubation revealed that as much as 20% of the substrate carbon could not be accounted for. 2. With [1-14C]ri...

Vitamin D and the incorporation of [1-14C]acetate into the organic acids of bone.

A relationship between vitamin D and citrate metabolism in bone was first observed by Dickens (1941), who found that the citrate content of bones from vitamin D-deficient animals was about 50% that of normal. This relationship was subsequently confirmed by Nicolaysen & Nordb0 (1943), Waasjo & Eeg-Larson (1951 a, b), Steenbock & Bellin (1953), and Carlsson & Hollunger (1954). In other work it ha...

Synthesis of 2-(4-methoxyphenyl)ethanol[ring-1-14C].